A study by Fang et al. showed that the overexpression of YTHDF2, mediated by the EGFR/SRC/ERK signal pathway, could expedite the m6A-dependent mRNA depletion of LXRα and HIVEP2, which facilitated cholesterol disturbances and the invasive growth of GBM [107]. The gene discussed is NR1H3; the disease is glioblastoma.