Additionally, GAB1 has been found to exert a positive role in HGF-mediated resistance to the V-Raf murine sarcoma viral oncogene homologue B (BRAF) kinase inhibitors, dabrafenib, and trametinib, and to the mitogen-activated protein kinase kinase (MEK) inhibitor, PD0325901, in BRAFV600E mutant melanoma [132]. Here, GAB1 is linked to melanoma.