There is no data that directly analyzed differences between Asian children and other ethnicities; however, the literature shows a higher prevalence of t(8;21) (RUNX1::RUNX1T1)-positive AML in Asian populations (approximately 30% compared to 12–14% of the U.S. or European patients) [1,21,22]. The gene discussed is RUNX1T1; the disease is acute myeloid leukemia.