Notably, the distribution on polyribosimal fractions of hemochromatosis (HFE), hemojuvelin (HJV), and hepcidin (HAMP) transcripts, all genes that were previously reported to respond to miR-122 [3], was found to be affected by the modulation of miR-122 levels (Supplementary Figure S1). This evidence concerns the gene HAMP and hemochromatosis type 1.