Literature mining in combination with GEO/TCGA database analysis showed that a subset of miR-122-responsive proteins, including G6PD, CEP55, KIF11, SLC1A5, EPS15L1, TK1, and CLIC1, were upregulated in liver tumor tissues of HCC patients (Supplementary Figure S8), with their increased expression being unfavorable in liver cancer (Supplementary Figure S9). This evidence concerns the gene TK1 and hepatocellular carcinoma.