Conditioned tumor cell medium treated with 10 μM 5-aza showed upregulation of 4 key cytokines—IL-6, IP-10 (CXCL10), KC (CXCL1), and RANTES (CCL5)—which activate both adaptive and innate immune responses (Figure 2E–G). The gene discussed is CXCL1; the disease is neoplasm.