CD34 and acute promyelocytic leukemia: A retrospective multicentric study on 58 patients undergoing autologous HSCT for APL at 21 institutions in the United States (U.S.)and Japan reported significantly longer times to neutrophil recovery (median 12 days vs. 9 days, p < 0.001) as well as lower median viable post-thaw CD34 + cell recovery of cryopreserved autologous stem cell products from patients with prior treatment with ATO, suggesting that ATO exposure prior to CD34 + cell harvest has deleterious effects on hematopoietic recovery after auto-HSCT.