BIRC5 and Burkitt lymphoma: Similarly, the coexpression of survivin and P-gp/ABCB1 was determined to be responsible for resistance to the conventional treatment of Burkitt lymphoma (BL), showing that treatment with verapamil, a P-gp/ABCB1 inhibitor, or Survivin siRNA suppressed the proliferation of all drug-resistant BL cells [45].