CD30—also known as Ki-1 or TNFRSF8—is a 120 kDa transmembrane glycoprotein receptor expressed in different types of B- and T-cell lymphomas, in plasma cells, in a subtype of activated macrophages, in myeloblasts in a subset of acute myeloid leukemia, and in some cases of myelodysplastic syndrome [22]. The gene discussed is TNFRSF8; the disease is myelodysplastic syndrome.