ERBB2 and neoplasm: Figure 1G shows that a single 1 × 108 PFU dose resulted in a complete cure. The 1 × 107 PFUs dose reduced the number of tumor nodules in the lungs in a dose-dependent manner (Figure 1H). Thus, a single dose of R-337 monotherapy was sufficient for a complete response. The T and B cell responses were very similar to those exerted by the multiple doses, i.e., the T cell response was addressed to the HER2 antigen as well as to the agnostic tumor antigens (Figure 1I), whereas the B response was addressed mainly to HER2 (Figure 1J).