PLAG1 and posterior cortical atrophy: Olivan et al. [147] suggested that miR-135b is involved in the bone homing of PC3-BM cells, affecting PCa bone metastasis via regulation of vesicle transport through interaction with t-SNAREs 1B (VIT1B), Janus kinase and microtubule interacting protein 2 (JAKMIP2), pleomorphic adenoma gene 1 (PLAG1), and platelet-derived growth factor subunit A (PDGFA), which are validated targets of miR-135b.