miR-141-3p is downregulated in PCa cell lines (22RV1, PC-3, VCaP, DU145, and LNCaP) compared with a healthy prostate cell line (RWPE-1) and is known to act as a bone metastasis suppressor by inhibiting NF-κB activation via targeting of TRAF5 and TRAF6 [153], which are responsible for mediating NF-κB activation by RANK [106]. The gene discussed is NFKB1; the disease is posterior cortical atrophy.