Of the latter, 27 presented diffuse LBCL, not otherwise specified (DLBCL, NOS); 12 were primary mediastinal large BCL (PMBCL); 7 were PCNSL; 5 were high-grade BCL with MYC and BCL2 and/or BCL6 rearrangement; 1 was EBV-positive diffuse large BCL, NOS; and 1 was BCL, unclassifiable, with features intermediate between DLBCL and classic Hodgkin lymphoma (gray zone B-cell lymphoma). This evidence concerns the gene BCL6 and primary central nervous system lymphoma.