MASP2 and IgA glomerulonephritis: A study by Wu et al. showed that mannan-binding lectin-associated serine protease 2 (MASP2) enrichment in uEVs from immunoglobulin A (IgA) nephropathy (IgAN) patients correlated with the level of urinary microalbumin and suggested MASP2 enrichment in uEVs may be a valuable biomarker for assessing the severity of renal injury as well as the prognosis of IgAN [92].