In contrast, we found that as the Gleason score increased from 3 to 5 in biopsied prostate cancer specimens, the GLS1 staining in the glandular compartment was maintained, but staining for GLS1, ω-amidase, and GTK in the stromal cell compartment now became apparent and increased with increasing Gleason score [1]. The gene discussed is GLS; the disease is Familial prostate cancer.