We, therefore, believe that our comprehensive pathological and functional changes that are identified after acute and long-term post-infection which are highly comparable to humans with acute and long-term post-SARS-CoV-2 infection outweigh the differences (e.g., concerns regarding the viral binding mechanisms, with CEACAM-1 in MHV-1 instead of ACE2 in SARS-CoV-2). The gene discussed is CEACAM1; the disease is infection.