Based on previous reports showing that the most obvious symptom of LGMD2H patients is skeletal muscle atrophy and that myopathic and dystrophic skeletal muscles in LGMD2H patients share features with atrophied skeletal muscles [119], studies on the pathophysiological roles of TRIM32 genetic variants in LGMD2H patients have been conducted, with particular attention paid to skeletal muscle atrophy. This evidence concerns the gene TRIM32 and Skeletal muscle atrophy.