Indeed, an aberrant HOXA5 expression contributes to anomalies and dysfunction in various organs, such as the thyroid gland, mammary glands, and ovaries, as well as affecting proliferation, differentiation, invasion, apoptosis, and other biological processes in multiple cancer types [5,6], where HOXA5 can function as both an oncogene and tumor suppressor [7]. Here, HOXA5 is linked to cancer.