The other subunit of ferritin, the ferritin light chain (FTL), is able to affect p27, p21, cyclin-dependent kinase 2 (CDK2), and retinoblastoma protein (pRB) expression, increasing the proliferative capacity of malignant mesothelioma cells and promoting the cell cycle [101]. The gene discussed is CDK2; the disease is malignant mesothelioma.