We observed that GR antagonism with EXI and RELA enhanced the sensitivity of chemoresistant PCa cells to DTX, consistent with our recent studies using a different SGRM (CORT108297) [25] and a previous report from another group showing that GR antagonism with mifepristone and cyproterone acetate reverts chemoresistance in DTX-resistant PCa cells [23]. Here, NR3C1 is linked to posterior cortical atrophy.