Mechanistic analysis revealed that miR-92a-2-5p in exosomes targets the 3′ untranslated region (3′UTR) of AR mRNA, leading to the suppression of AR translation and subsequent modulation of the PHLPP/p-AKT/β-catenin signaling pathway, resulting in increased invasion of HCC cells. The gene discussed is AKT1; the disease is hepatocellular carcinoma.