PTGS2 and hereditary clear cell renal cell carcinoma: The results revealed that the downregulation of PTGS2 expression was significantly associated with folate biosynthesis, dorsoventral axis formation, renal cell carcinoma, regulation of autophagy, glycosphingolipid biosynthesis (lacto and neolacto series), pantothenate and coenzyme A (CoA) biosynthesis, and O-glycan biosynthesis pathways.