Another point connecting diabetes with coronaviruses is that both SARS-CoV (severe acute respiratory syndrome coronavirus) and SARS-CoV-2 (the causative agent of COVID-19) can enter respiratory tract cells by exploiting the angiotensin-converting enzyme 2 (ACE2) and binding to the spike protein on the virion surface [10]; the effects of this enzyme are multifold, and it also has a major role in micro and macrovascular complications in subjects with diabetes [11]. This evidence concerns the gene ACE2 and COVID-19.