There are many other proteins with pro-angiogenic activity currently under investigation in gliomas, such as the transmembrane protein vasorin [56], Ras homolog family member 1 (Rho1) [57], and chemokine receptor 2 (CXCR2), along with its ligand CXCL2 [60]. The gene discussed is CXCL2; the disease is central nervous system cancer.