MBD2 and glioblastoma: For other demethylases of N6-methyladenosine such as the AlkB homologues 1 and 5 (ALKBH1 and ALKBH5) in glioblastomas, marked overexpression along with concomitant histone changes such as triple methylation of histone 3 at position 9 (H3K9me3) has been reported.