In this study, fibroblasts were acquired from a patient either homozygous for the TREM2 p.T66M mutation or the TREM2 p.w50C mutation, both of which are missense mutations known to cause frontotemporal dementia-like syndrome and Nasu-Hakola disease, respectively [97]. The gene discussed is TREM2; the disease is Nasu-Hakola disease.