PRKN and Parkinson disease: Mutations in genes such as PINK1, PRKN, DJ-1, ATP13A2, LRRK2, SNCA, and VPS35 are commonly found in PD, and dysfunctions in these genes affect essential processes in the mitochondrial quality control system that ensure mitochondrial function, like fusion and fission, biogenesis, and mitophagy [5,7].