To examine the role of CRF and urocortins in the social behavior of rats, male or female rats of different strains were injected with ICV directly into the BLA or BNST with CRF or Ucn1, and they were then investigated in a social interaction test for anxiety-like and social behavior [61,62,63,64,65,66,67,68,69] (Table 1). The gene discussed is CRH; the disease is Anxiety.