CRP and systemic inflammatory response syndrome: On the other hand, an analysis by Akdeniz et al. [38] showed that diabetes, acute phase proteins (CRP), platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte count, urinary white blood cell count, stone size, mean ASA score, type of surgery, duration of surgery, mean hemoglobin drop, length of hospital stay, blood transfusion, and complication rate were associated with SIRS development after percutaneous nephrolithotomy, but age, gender, BMI, and location of stones were not [38].