BDKRB1 and acute kidney injury: In this work, we have demonstrated the important role of the B1 receptor in AKI development, as we could observe a lower level of creatinine, urea, and injury scores in B1KO animals as well as in animals that received the treatment with B1 antagonist, suggesting the B1R’s contribution to the injury kidney mechanism and also the kidney-protected role of the B1R antagonist.