ADIPOQ and chronic kidney disease: By univariate linear regression analysis, we detected a negative correlation between logarithmically transformed BUN (log-BUN, r = −0.244, p = 0.005), and a positive correlation between serum adiponectin (r = 0.512, p < 0.001) and eGFR (r = 0.230, p = 0.008), respectively, and VRI values in patients with CKD (Table 2).