ADIPOQ and chronic kidney disease: In addition, adjustments for variables significantly associated with VRI values in univariate linear regression analysis revealed a significant and independent negative, and a significant independent positive association between log-BUN (standardized β = −0.176, adjusted R2 change = 0.025; p = 0.021), and adiponectin (standardized β = 0.487, adjusted R2 change = 0.256; p < 0.001), respectively, and VRI values in patients with CKD by multivariate stepwise linear regression analysis (Table 2).