Further, the WES analysis detected the following: (i) the FCRL3 (NM_052939.4):c.958T>A variant segregated in patient 34 and her sister (patient 35); (ii) the MAP3K4 (NM_005922.4):c.3590_3598dupCTGCTGCTG variant detected in patient 28 segregated in two other members of her family (patients 63 and 64 (respectively, her mother and aunt)), both diagnosed with EM. The gene discussed is MAP3K4; the disease is erythema multiforme.