Research conducted by Zhong et al. demonstrated that antibiotic exposure leads to an enrichment of gut Proteobacteria, increased gut permeability, and elevated levels of intra-tumoral lipopolysaccharide (LPS), which promote the development of prostate cancer through the NF-κB-IL6-STAT3 axis in mice [178]. The gene discussed is IL6; the disease is Familial prostate cancer.