RNF216P1 and hepatocellular carcinoma: (Fig. 6b), We then verified the target gene, and the results showed that: The expression level of SNHG3 in hepatoma cell line HepG2 was significantly higher than that of normal liver cell line LO2 (P < 0.05), and the expression levels of SNHG6, SNHG12 and RNF216P1 in HepG2 and Huh7 hepatoma cell lines were significantly higher than that of LO2 (P < 0.05).