VSIG2 and cancer: TIMER2.0 database was used for pan-cancer analysis, which showed significant differential expression of VSIG2 in BRCA, ESCA, HNSC, KIRC, KIRP, LUAD, LUSC, PAAD, STAD, UCEC, THCA, READ, PRAD, LIHC, GBM, and COAD (Fig. 1A).