NPPB and Left atrial enlargement: In addition, elevated serum NT-proBNP at 750 pg/mL or more is associated with a higher serum creatinine with a median value of 1.04 mg/dL (IQR 0.8–1.3, P = 0.002), newly diagnosed atrial fibrillation (NDAF) (44.4%, P = 0.002), cardioembolism (51.9%, P = 0.001), left atrial enlargement (LAE) (25.9%, P = 0.03) and enlarged left atrial diameter (mean LADM, 3.9 ± 0.7 cm, P = 0.04).