KCTD12 and cholangiocarcinoma: KCTD12 mRNA expression levels in cholangiocarcinoma (CHOL), glioblastoma multiforme (GBM), kidney renal papillary cell carcinoma (KIRP), lymphoid neoplasm diffuse large B cell lymphoma (DLBC), brain lower-grade glioma (LGG), and acute myeloid leukemia (LAML) were higher than those in normal tissues (P < 0.05) (Fig. 1a,b).