The expression levels of KCTD12 protein in BRCA, ovarian serous cystadenocarcinoma (OV), COAD, LUAD, liver hepatocellular carcinoma (LIHC), UCEC, and HNSC tumor tissues were lower than those in the corresponding normal tissues (P < 0.001) (Fig. 1c) but were elevated in PAAD, GBM (P < 0.001) (Fig. 1c), and KIRC (P < 0.001) (Fig. S1). Here, KCTD12 is linked to colon adenocarcinoma.