GPT and chronic kidney disease: In model II, after adjusting for important covariates such as CKD, CKD prognosis risk, fasting blood glucose, HbA1c, ALT, AST, Cr, uric acid, TG, HDL, drinking habits, smoking status, hypertension, BMI, and PHQ-9 score, linear regression analysis revealed that nocturia was still associated with a decrease of 4.0 ml/min/1.73 m2 in eGFR compared to individuals without nocturia.