As CHK1 is a key Ser/Thr kinase involved in the control of cell cycle checkpoints and DNA damage response, and may serve as an ideal therapeutic drug target [3], it would be intriguing to explore the underlying correlation between BRD7 and CHK1 in tumor cells and the role of the BRD7-CHK1 axis in chemotherapy. The gene discussed is CHEK1; the disease is neoplasm.