NR1D1 and tauopathy: As we observed sex-dependent effects of microglial REV-ERBα deletion on tauopathy in PS19 mice (Figs. 2, 3), we hypothesized that the effects of microglial REV-ERBα KO on LD accumulation and microglial tau phagocytosis might vary in a sex-dependent manner in the presence of tau.