CDKN2A and neoplasm: Our study did not aim at comparing histopathology with PCR, as both methods have different advantages; thus, the histopathological method specifically analyzes a tumor area, serially sectioned, immunolabeled with the three anti-p16/HPV/Ki67 antibodies studied, thus being able to perform descriptive statistical studies, whereas molecular methods can detail whether the genome is episomal or integrated.