A prior report published in Cancer Discovery demonstrated that venetoclax increased the T cell infiltrate of MC38 colorectal cancers subcutaneously (s.c.)implanted in C57BL/6 mice (or that of CT26 mice implanted in BALB/c mice), sensitizing such tumors to PD-1 or PD-L1 blockade (30). The gene discussed is CD274; the disease is colorectal cancer.