These metabolites were assessed for different bioactivities, including cytotoxic, antimicrobial, antioxidant, antiviral, anti-obesity, anti-inflammation, immunosuppression, anti-diabetic, protein tyrosine phosphatase 1B (PTP1B) inhibition, and anti-nematode activities (Figure 18). This evidence concerns the gene PTPN1 and obesity due to melanocortin 4 receptor deficiency.