Also, it is noteworthy that ADAMTS1 expression is increased by Angiotensin II (AngII) and other factors involved in vascular remodeling, representing its potential role in cardiac and vascular remodeling [57], causing clinical or subclinical ischemic cardiomyopathy, coronary artery disease, valvular or aortic diseases, and eventually affecting myocardial structure and function. Here, ADAMTS1 is linked to ischemic cardiomyopathy.