ERBB2 and neoplasm: For example, X-ray high-absorption gold nanoparticles (GNPs) can be used as a computed tomography (CT) imaging enhancer for in vivo angiography, since GNPs (polymers and mRNA) or their targeted modification (e.g., with epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), RGD peptide, folic acid) can accumulate in tumor tissues and enhance image development [40,71,72].