Lastly, in the case of CAN patients, increased levels of AGT, Calreticulin (CALR), Dystroglycan 1 (DAG1), FABP4, Family with Sequence Similarity 151 Member A (FAM151A), FAM3C, KIT Ligand (KITLG), LRG1, Lumican (LUM), and Serpin Family A Member 2 (SERPINA2P) were observed [4,144]. The gene discussed is LUM; the disease is Crouzon syndrome-acanthosis nigricans syndrome.