Specific autoantibodies such as anti-alpha enolase, anti-GH, anti-PGSF1a and 2, anti-chorionic somatomammotropin hormone (HPL), anti-prohormone convertase (PC), anti-PIT-1, anti-POMC, anti-alpha rad guanine nucleotide dissociation inhibitor, anti-secretogranin, anti-TDRD6, and anti-T-PIT have been found in patients with hypophysitis and hypopituitarism [36,43,44]. Here, IRF6 is linked to hypophysitis.