A sub-analysis of a prospective randomized AVOCADO (Aspirin Vs./Or Clopidogrel in Aspirin-resistant Diabetics inflammation Outcomes) trial with 273 type 2 diabetic participants demonstrated that participants with AF at baseline (12%) had higher levels of serum adiponectin compared to those without AF at baseline [60]. This evidence concerns the gene ADIPOQ and atrial fibrillation.