In the context of RET-mutant medullary thyroid carcinoma (MTC), it is recommended to use selpercatinib as a kinase inhibitor targeting various forms of rearranged during transfection (RET), including wildtype RET, multiple mutated RET isoforms, VEGFR1, and VEGFR3. This evidence concerns the gene FLT1 and medullary thyroid gland carcinoma.