Although recent clinical research highlights the potential beneficial effects of neoadjuvant (preoperative) treatments, for example with anti-HER2 or anti-EGFR antibodies in BC [92], these are rarely administered during the IPP, with the neoadjuvant treatment regimen ending 3 weeks or more before surgery, and adjuvant therapy starting months after it [93,94,95]. Here, ERBB2 is linked to breast cancer.