Since ALOX15 is essential for lipid peroxidation in membranes, Alox15 knockout (KO) mice were employed for AAV‐mediated overexpression of A53T by stereotactic injection technique, in order to investigate the role of ALOX15 in stress‐induced PD susceptibility (Figure 4a,b). The gene discussed is ALOX15; the disease is Parkinson disease.