PTPRC and neoplasm: In addition, while the percentage of DCs within tumor-infiltrating CD45+ cells was lower in αCD40-treated tumors, the contribution of CD81+migcDC1s to the overall DC pool increased (Figures 4C, S6A, B), suggesting that αCD40 further induced cDC1 to adopt an activated migcDC1 state as has been shown in other tumor models (10).