The reported lead keratoconus GWAS variant (rs142493024, p-value = 9 × 10−12) at locus 35 (Hardcastle et al., 2021) is a low-frequency variant missing from summary statistics, along with the other intronic COL6A1 variants forming one of four CS delineated at CRF locus 115 by DAP-G (cs1), SuSiE (cs1), and FINEMAP (cs4) (Supplementary Table S4). Here, COL6A1 is linked to keratoconus.